The scope of the PONTE project is to enable the semantic interoperability between clinical research and medical practice information systems for the intelligent selection of patients eligible to participate in clinical trials and for the enhanced design and efficient management of clinical trials conduction. The PONTE structure is dynamic and flexible to support the realisation of proposed solution and involves a layered project structure following the classical waterfall model starting with scenarios, requirements and expected outcome, followed by architecture and design/specification, implementation, integration and evaluation of the various aspects.
Within this concept, seven major activities have been identified that are represented in seven Work Packages, the interaction among which is depicted in the figure below:
PONTE WP Structure
- WP1a and WP1b cover all necessary project and technical management activities respectively.
- WP2 sets the ground for the PONTE platform design and implementation. Besides the provision of requirements and use cases this Work Package will define the key business cases, analyse the security and privacy aspects and perform a thorough market analysis. It should be noted that in an effort to effectively capture the PONTE platform requirements by all the potential PONTE users, we shall use our network of contacts both in academia research and in pharmaceutical companies and perform a thorough requirements analysis. Moreover, the definition of the validation plan will provide a valuable basis for the integrated system evaluation.
- WP3 will concentrate on specifying the overall architecture. Within this WP, the PONTE user and security requirements as well as scenarios provide the basis for system requirements extraction and the definition of the overall architecture which has the primary goal to define the key building blocks, to specify the system and thus guide the activities within WP4 and WP5.
- WP4, based on the global specifications from WP3, will define semantic data and metadata representations for clinical trials and a specification language with high expressive power which will cover the different fields involved.
- WP5 will develop the novel object-oriented search engine and framework services based on the WP4 semantic data representation and under the guidelines from WP3.
- WP6 involves the integration of the developments done in WP4 and WP5. Further, this WP will carry out the platform evaluation based on the requirements and validation process and evaluation criteria specified within T2.3 and T2.4.
- WP7 includes the dissemination, standardisation, exploitation and collaboration activities related to PONTE innovative research work and results.